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Electrophysiological Properties of Motor Neurons in a Mouse Model of Severe Spinal Muscular Atrophy: In Vitro versus In Vivo Development

We examined the electrophysiological activity of motor neurons from the mouse model of severe spinal muscular atrophy (SMA) using two different methods: whole cell patch clamp of neurons cultured from day 13 embryos; and multi-electrode recording of ventral horns in spinal cord slices from pups on p...

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Autori principali: Zhang, Hongmei, Robinson, Natallia, Wu, Chiayen, Wang, Wenlan, Harrington, Melissa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908141/
https://ncbi.nlm.nih.gov/pubmed/20657731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011696
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