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Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1

Proper neural circuitry requires that growth cones, motile tips of extending axons, respond to molecular guidance cues expressed in the developing organism. However, it is unclear how guidance cues modify the cytoskeleton to guide growth cone pathfinding. Here we show acute treatment with two attrac...

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Autori principali: Marsick, Bonnie M., Flynn, Kevin C., Santiago-Medina, Miguel, Bamburg, James R., Letourneau, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908028/
https://ncbi.nlm.nih.gov/pubmed/20506164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20800
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