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Opioids, Pain, the Brain, and Hyperkatifeia: A Framework for the Rational Use of Opioids for Pain

OBJECTIVE: Opioids have relieved more human suffering than any other medication, but their use is still fraught with significant concerns of misuse, abuse, and addiction. This theoretical article explores the hypothesis that opioid misuse in the context of pain management produces a hypersensitivity...

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Detalhes bibliográficos
Main Authors: Shurman, Joseph, Koob, George F., Gutstein, Howard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907890/
https://ncbi.nlm.nih.gov/pubmed/20545871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1526-4637.2010.00881.x
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