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Oncolytic measles viruses encoding interferon β and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy

Mesothelioma usually leads to death within 8–14 months of diagnosis. To increase the potency of oncolytic measles viruses (MVs) for mesothelioma therapy, we inserted the interferon β (IFNβ) gene alone or with the human thyroidal sodium iodide symporter (NIS) gene into attenuated MV of the Edmonston...

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Detalhes bibliográficos
Main Authors: Li, H, Peng, K-W, Dingli, D, Kratzke, R A, Russell, S J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907639/
https://ncbi.nlm.nih.gov/pubmed/20379224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.10
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