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Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport

Transport of material and signals between extensive neuronal processes and the cell body is essential to neuronal physiology and survival. Slowing of axonal transport has been shown to occur before the onset of symptoms in amyotrophic lateral sclerosis (ALS). We have previously shown that several fa...

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Autors principals: Shi, Ping, Ström, Anna-Lena, Gal, Jozsef, Zhu, Haining
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907440/
https://ncbi.nlm.nih.gov/pubmed/20510358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.05.008
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