Interaction of Amyotrophic Lateral Sclerosis (ALS)-related Mutant Copper-Zinc Superoxide Dismutase with the Dynein-Dynactin Complex Contributes to Inclusion Formation

An important consequence of protein misfolding related to neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), is the formation of proteinaceous inclusions or aggregates within the central nervous system. We have previously shown that several familial ALS-linked copper-zinc sup...

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Detalhes bibliográficos
Main Authors: Ström, Anna-Lena, Shi, Ping, Zhang, Fujian, Gal, Jozsef, Kilty, Renee, Hayward, Lawrence J., Zhu, Haining
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504878/
https://ncbi.nlm.nih.gov/pubmed/18515363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800276200
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