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LRP5 Is Required for Vascular Development in Deeper Layers of the Retina

BACKGROUND: The low-density lipoprotein receptor-related protein 5 (LRP5) plays an important role in the development of retinal vasculature. LRP5 loss-of-function mutations cause incomplete development of retinal vessel network in humans as well as in mice. To understand the underlying mechanism for...

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Detalhes bibliográficos
Main Authors: Xia, Chun-hong, Yablonka-Reuveni, Zipora, Gong, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907392/
https://ncbi.nlm.nih.gov/pubmed/20652025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011676
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