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Structures of minimal catalytic fragments of topoisomerase V reveals conformational changes relevant for DNA binding
Topoisomerase V is an archaeal type I topoisomerase that is unique among topoisomerases due to presence of both topoisomerase and DNA repair activities in the same protein. It is organized as an N-terminal topoisomerase domain followed by 24 tandem helix hairpin helix (HhH) motifs. Structural studie...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907367/ https://ncbi.nlm.nih.gov/pubmed/20637419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.03.006 |
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