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Tissue Doppler Imaging Consistently Detects Myocardial Contraction and Relaxation Abnormalities, Irrespective of Cardiac Hypertrophy, in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is diagnosed clinically by the presence of left ventricular hypertrophy (LVH). However, LVH is absent in a significant number of genotype-positive patients. Because myocyte dysfunction and disarray are the primary abnormalities in HCM, we reasoned that t...

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Detalhes bibliográficos
Main Authors: Nagueh, Sherif F., Kopelen, Helen A., Lim, Do-Sun, Zoghbi, William A., Quiñones, Miguel A., Roberts, Robert, Marian, Ali J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907266/
https://ncbi.nlm.nih.gov/pubmed/10993850
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