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Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism

Inflammation is a hallmark of many diseases, such as atherosclerosis, chronic obstructive pulmonary disease, arthritis, infectious diseases, and cancer. Although steroids and cyclooxygenase inhibitors are effective antiinflammatory therapeutical agents, they may cause serious side effects. Therefore...

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Bibliographische Detailangaben
Hauptverfasser: Jeon, Kye-Im, Xu, Xiangbin, Aizawa, Toru, Lim, Jae Hyang, Jono, Hirofumi, Kwon, Dong-Seok, Abe, Jun-ichi, Berk, Bradford C., Li, Jian-Dong, Yan, Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906898/
https://ncbi.nlm.nih.gov/pubmed/20448200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914414107
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