Single-base resolution mapping of H1–nucleosome interactions and 3D organization of the nucleosome

Despite the key role of the linker histone H1 in chromatin structure and dynamics, its location and interactions with nucleosomal DNA have not been elucidated. In this work we have used a combination of electron cryomicroscopy, hydroxyl radical footprinting, and nanoscale modeling to analyze the str...

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Autores principales: Syed, Sajad Hussain, Goutte-Gattat, Damien, Becker, Nils, Meyer, Sam, Shukla, Manu Shubhdarshan, Hayes, Jeffrey J., Everaers, Ralf, Angelov, Dimitar, Bednar, Jan, Dimitrov, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906896/
https://ncbi.nlm.nih.gov/pubmed/20457934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000309107
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