Single-base resolution mapping of H1–nucleosome interactions and 3D organization of the nucleosome

Despite the key role of the linker histone H1 in chromatin structure and dynamics, its location and interactions with nucleosomal DNA have not been elucidated. In this work we have used a combination of electron cryomicroscopy, hydroxyl radical footprinting, and nanoscale modeling to analyze the str...

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Autors principals: Syed, Sajad Hussain, Goutte-Gattat, Damien, Becker, Nils, Meyer, Sam, Shukla, Manu Shubhdarshan, Hayes, Jeffrey J., Everaers, Ralf, Angelov, Dimitar, Bednar, Jan, Dimitrov, Stefan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906896/
https://ncbi.nlm.nih.gov/pubmed/20457934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000309107
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