טוען...
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
Macrophages respond to cytosolic nucleic acids by activating cysteine protease caspase-1 within a complex called the inflammasome. Subsequent cleavage and secretion of proinflammatory cytokines IL-1β and IL-18 are critical for innate immunity. Here, we show that macrophages from mice lacking absent...
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| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906881/ https://ncbi.nlm.nih.gov/pubmed/20457908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003738107 |
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