Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques

Adjuvant effects on innate as well as adaptive immunity may be critical for inducing protection against mucosal HIV and simian immunodeficiency virus (SIV) exposure. We therefore studied effects of Toll-like receptor agonists and IL-15 as mucosal adjuvants on both innate and adaptive immunity in a p...

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Bibliographic Details
Main Authors: Sui, Yongjun, Zhu, Qing, Gagnon, Susan, Dzutsev, Amiran, Terabe, Masaki, Vaccari, Monica, Venzon, David, Klinman, Dennis, Strober, Warren, Kelsall, Brian, Franchini, Genoveffa, Belyakov, Igor M., Berzofsky, Jay A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906837/
https://ncbi.nlm.nih.gov/pubmed/20457926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911932107
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