Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Systemic lupus erythematosus (SLE) is an autoimmune disease in which patients develop autoantibodies to DNA, histones, and often to neutrophil proteins. These form immune complexes that are pathogenic and may cause lupus nephritis. In SLE patients, infections can initiate flares and are a major caus...

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Bibliografiske detaljer
Main Authors: Hakkim, Abdul, Fürnrohr, Barbara G., Amann, Kerstin, Laube, Britta, Abed, Ulrike Abu, Brinkmann, Volker, Herrmann, Martin, Voll, Reinhard E., Zychlinsky, Arturo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906830/
https://ncbi.nlm.nih.gov/pubmed/20439745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909927107
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