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The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives
Recently, we constructed and characterized isogenic tcdA and tcdB mutants of a virulent Clostridium difficile strain and used a hamster model of disease to demonstrate that toxin B, not toxin A, is essential for virulence of this emerging pathogen. Earlier studies had shown that purified toxin A alo...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906822/ https://ncbi.nlm.nih.gov/pubmed/20664812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.1.1.10768 |
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