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Role of Helix B Residues in Interfacial Activation of a Bacterial Phosphatidylinositol-Specific Phospholipase C
The Bacillus thuringiensis phosphatidylinositol-specific phospholipase C (PI-PLC), an interfacial enzyme associated with prokaryotic infectivity, is activated by binding to zwitterionic surfaces, particularly phosphatidycholine (PC). Two tryptophan residues (Trp47 in the two-turn helix B and Trp242...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906773/ https://ncbi.nlm.nih.gov/pubmed/18345643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702269u |
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