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Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi Syndrome
RNA transcripts encoding the 2C-subtype of serotonin (5HT(2C)) receptor undergo up to five adenosine-to-inosine editing events to encode twenty-four protein isoforms. To examine the effects of altered 5HT(2C) editing in vivo, we generated mutant mice solely expressing the fully-edited (VGV) isoform...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906772/ https://ncbi.nlm.nih.gov/pubmed/20394819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.04.004 |
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