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Protein N-Terminal Processing: Substrate Specificity of Escherichia coli and Human Methionine Aminopeptidases

Methionine aminopeptidase (MetAP) catalyzes the hydrolytic cleavage of the N-terminal methionine from newly synthesized polypeptides. The extent of methionyl removal from a protein is dictated by its N-terminal peptide sequence. Earlier studies revealed that MetAPs require amino acids containing sma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiao, Qing, Zhang, Feiran, Nacev, Benjamin A., Liu, Jun O., Pei, Dehua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906754/
https://ncbi.nlm.nih.gov/pubmed/20521764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1005464
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