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Protein N-Terminal Processing: Substrate Specificity of Escherichia coli and Human Methionine Aminopeptidases
Methionine aminopeptidase (MetAP) catalyzes the hydrolytic cleavage of the N-terminal methionine from newly synthesized polypeptides. The extent of methionyl removal from a protein is dictated by its N-terminal peptide sequence. Earlier studies revealed that MetAPs require amino acids containing sma...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906754/ https://ncbi.nlm.nih.gov/pubmed/20521764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1005464 |
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