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Brain dystrophin-glycoprotein complex: Persistent expression of beta-dystroglycan, impaired oligomerization of Dp71 and up-regulation of utrophins in animal models of muscular dystrophy

BACKGROUND: Aside from muscle, brain is also a major expression site for dystrophin, the protein whose abnormal expression is responsible for Duchenne muscular dystrophy. Cognitive impairments are frequently associated with this genetic disease, we therefore studied the fate of brain and skeletal mu...

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Detalhes bibliográficos
Main Authors: Culligan, Kevin, Glover, Louise, Dowling, Paul, Ohlendieck, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC29067/
https://ncbi.nlm.nih.gov/pubmed/11178104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-2-2
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