Altered plasmodial surface anion channel activity and in vitro resistance to permeating antimalarial compounds

Erythrocytes infected with malaria parasites have increased permeability to various solutes. These changes may be mediated by an unusual small conductance ion channel known as the plasmodial surface anion channel (PSAC). While channel activity benefits the parasite by permitting nutrient acquisition...

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Main Authors: Lisk, Godfrey, Pain, Margaret, Sellers, Morgan, Gurnev, Philip A., Pillai, Ajay D., Bezrukov, Sergey M., Desai, Sanjay A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906662/
https://ncbi.nlm.nih.gov/pubmed/20451492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.04.013
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