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Novel in vivo model of inducible multidrug resistance in acute lymphoblastic leukemia with chromosomal translocation t(4;11)
Acute lymphoblastic leukemia (ALL) with translocation t(4;11) is found in 60–85% of infants with ALL and is often refractory to conventional chemotherapeutics after relapse. Using the t(4;11) ALL line SEM, we evaluated chemotherapy resistance in NOD.CB17-Prkdcscid/J mice. SEM cells were injected int...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906616/ https://ncbi.nlm.nih.gov/pubmed/20381955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.03.017 |
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