Regulation of human metabolism by hypoxia-inducible factor

The hypoxia-inducible factor (HIF) family of transcription factors directs a coordinated cellular response to hypoxia that includes the transcriptional regulation of a number of metabolic enzymes. Chuvash polycythemia (CP) is an autosomal recessive human disorder in which the regulatory degradation...

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Main Authors: Formenti, Federico, Constantin-Teodosiu, Dumitru, Emmanuel, Yaso, Cheeseman, Jane, Dorrington, Keith L., Edwards, Lindsay M., Humphreys, Sandy M., Lappin, Terence R. J., McMullin, Mary F., McNamara, Christopher J., Mills, Wendy, Murphy, John A., O'Connor, David F., Percy, Melanie J., Ratcliffe, Peter J., Smith, Thomas G., Treacy, Marilyn, Frayn, Keith N., Greenhaff, Paul L., Karpe, Fredrik, Clarke, Kieran, Robbins, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906567/
https://ncbi.nlm.nih.gov/pubmed/20616028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002339107
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