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A Comparative Approach Linking Molecular Dynamics of Altered Peptide Ligands and MHC with In Vivo Immune Responses

BACKGROUND: The recognition of peptide in the context of MHC by T lymphocytes is a critical step in the initiation of an adaptive immune response. However, the molecular nature of the interaction between peptide and MHC and how it influences T cell responsiveness is not fully understood. RESULTS: We...

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Detalhes bibliográficos
Main Authors: Knapp, Bernhard, Omasits, Ulrich, Schreiner, Wolfgang, Epstein, Michelle M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906508/
https://ncbi.nlm.nih.gov/pubmed/20657836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011653
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