Sodium butyrate enhances the cytotoxic effect of cisplatin by abrogating the cisplatin imposed cell cycle arrest

BACKGROUND: Histone deacetylase inhibitors have been proposed as potential enhancers of the cytotoxic effect of cisplatin and other anticancer drugs. Their application would permit the use of lower therapeutic doses and reduction of the adverse side effects of the drugs. However, the molecular mecha...

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Hlavní autoři: Koprinarova, Miglena, Markovska, Petya, Iliev, Ivan, Anachkova, Boyka, Russev, George
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906439/
https://ncbi.nlm.nih.gov/pubmed/20576112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-11-49
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