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Sodium butyrate enhances the cytotoxic effect of cisplatin by abrogating the cisplatin imposed cell cycle arrest

BACKGROUND: Histone deacetylase inhibitors have been proposed as potential enhancers of the cytotoxic effect of cisplatin and other anticancer drugs. Their application would permit the use of lower therapeutic doses and reduction of the adverse side effects of the drugs. However, the molecular mecha...

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Main Authors: Koprinarova, Miglena, Markovska, Petya, Iliev, Ivan, Anachkova, Boyka, Russev, George
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906439/
https://ncbi.nlm.nih.gov/pubmed/20576112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-11-49
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