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Regulation of lipid droplet turnover by ubiquitin ligases
Mutation of the protein spartin is a cause of one form of spastic paraplegia. Spartin interacts with ubiquitin ligases of the Nedd4 family, and a recent report in BMC Biology now shows that it acts as an adaptor to recruit and activate the ubiquitin ligase AIP4 onto lipid droplets, leading to the ub...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906420/ https://ncbi.nlm.nih.gov/pubmed/20646264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-8-94 |
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