Canonical Transient Receptor Potential 6 (TRPC6), a Redox-regulated Cation Channel

This study examined the effect of H(2)O(2) on the TRPC6 channel and its underlying mechanisms using a TRPC6 heterologous expression system. In TRPC6-expressing HEK293T cells, H(2)O(2) significantly stimulated Ca(2+) entry in a dose-dependent manner. Electrophysiological experiments showed that H(2)O...

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Autors principals: Graham, Sarabeth, Ding, Min, Ding, Yanfeng, Sours-Brothers, Sherry, Luchowski, Rafal, Gryczynski, Zygmunt, Yorio, Thomas, Ma, Haiying, Ma, Rong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906337/
https://ncbi.nlm.nih.gov/pubmed/20501650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093500
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