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Homodimerization Is Essential for the Receptor for Advanced Glycation End Products (RAGE)-mediated Signal Transduction

The receptor for advanced glycation end products (RAGE) is a pattern-recognition receptor that binds to diverse ligands and initiates a downstream proinflammatory signaling cascade. RAGE activation has been linked to diabetic complications, Alzheimer disease, infections, and cancers. RAGE is known t...

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Autors principals: Zong, Hongliang, Madden, Angelina, Ward, Micheal, Mooney, Mark H., Elliott, Christopher T., Stitt, Alan W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906307/
https://ncbi.nlm.nih.gov/pubmed/20504772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133827
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