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The Extracellular K(+) Concentration Dependence of Outward Currents through Kir2.1 Channels Is Regulated by Extracellular Na(+) and Ca(2+)
It has been known for more than three decades that outward Kir currents (I(K1)) increase with increasing extracellular K(+) concentration ([K(+)](o)). Although this increase in I(K1) can have significant impacts under pathophysiological cardiac conditions, where [K(+)](o) can be as high as 18 mm and...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906305/ https://ncbi.nlm.nih.gov/pubmed/20495007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121186 |
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