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Enhanced Endocannabinoid Signaling Elevates Neuronal Excitability in Fragile X Syndrome

Fragile X syndrome (FXS) results from deficiency of fragile X mental retardation protein (FMRP). FXS is the most common heritable form of mental retardation, and is associated with the occurrence of seizures. Factors responsible for initiating FXS-related hyperexcitability are poorly understood. Man...

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Autori principali: Zhang, Longhua, Alger, Bradley E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906112/
https://ncbi.nlm.nih.gov/pubmed/20410124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0795-10.2010
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