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Role of Presenilins in Neuronal Calcium Homeostasis
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder. Familial AD (FAD) mutations in presenilins have been linked to calcium (Ca(2+)) signaling abnormalities. To explain these results, we previously proposed that presenilins function as endoplasmic reticulum (ER...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906098/ https://ncbi.nlm.nih.gov/pubmed/20573903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1554-10.2010 |
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