POLG1 polyglutamine tract variants associated with Parkinson’s disease

A possible role of allelic variation of the mitochondrial DNA polymerase gamma (POLG1) gene in Parkinson’s disease (PD) has been suggested. First, POLG1 missense mutations have been found in patients with familial parkinsonism and mitochondrial myopathy. Second, increased frequency of rare alleles o...

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Bibliographic Details
Main Authors: Eerola, Johanna, Luoma, Petri T., Peuralinna, Terhi, Scholz, Sonja, Paisan-Ruiz, Coro, Suomalainen, Anu, Singleton, Andrew B., Tienari, Pentti J.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905783/
https://ncbi.nlm.nih.gov/pubmed/20399836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.04.021
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