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POLG1 polyglutamine tract variants associated with Parkinson’s disease

A possible role of allelic variation of the mitochondrial DNA polymerase gamma (POLG1) gene in Parkinson’s disease (PD) has been suggested. First, POLG1 missense mutations have been found in patients with familial parkinsonism and mitochondrial myopathy. Second, increased frequency of rare alleles o...

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Detalhes bibliográficos
Main Authors: Eerola, Johanna, Luoma, Petri T., Peuralinna, Terhi, Scholz, Sonja, Paisan-Ruiz, Coro, Suomalainen, Anu, Singleton, Andrew B., Tienari, Pentti J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905783/
https://ncbi.nlm.nih.gov/pubmed/20399836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.04.021
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