A Role for the Mevalonate Pathway in the Induction of Subtype Crossreactive Immunity to Influenza A Virus by Human γδ T Lymphocytes

The major γδ T cell subset in the human peripheral blood expresses the Vγ9δ2 TCR and recognizes non-peptidic prenyl pyrophosphate antigens such as isopentylpyrophosphate (IPP). Upon activation the γδ T cells rapidly secrete antiviral cytokines similar to classical memory αβ T cells. Here we have inv...

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Hlavní autoři: Jameson, Julie M., Cruz, John, Costanzo, Anne, Terajima, Masanori, Ennis, Francis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905741/
https://ncbi.nlm.nih.gov/pubmed/20483407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2010.04.013
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