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A Role for the Mevalonate Pathway in the Induction of Subtype Crossreactive Immunity to Influenza A Virus by Human γδ T Lymphocytes
The major γδ T cell subset in the human peripheral blood expresses the Vγ9δ2 TCR and recognizes non-peptidic prenyl pyrophosphate antigens such as isopentylpyrophosphate (IPP). Upon activation the γδ T cells rapidly secrete antiviral cytokines similar to classical memory αβ T cells. Here we have inv...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905741/ https://ncbi.nlm.nih.gov/pubmed/20483407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2010.04.013 |
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