Glucose Regulation of Thrombospondin and Its Role in the Modulation of Smooth Muscle Cell Proliferation

Smooth muscle cells (SMC) maintained in high glucose are more responsive to IGF-I than those in normal glucose. There is significantly more thrombospondin-1 (TSP-1) in extracellular matrix surrounding SMC grown in 25 mM glucose. In this study we investigated 1) the mechanism by which glucose regulat...

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Détails bibliographiques
Auteurs principaux: Maile, Laura A., Allen, Lee B., Hanzaker, Christopher F., Gollahon, Katherine A., Dunbar, Paul, Clemmons, David R.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905704/
https://ncbi.nlm.nih.gov/pubmed/20689700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/617052
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