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Ubiquitination Acutely Regulates Presynaptic Neurotransmitter Release in Mammalian Neurons

The ubiquitin proteasome system (UPS) plays a crucial role in modulating synaptic physiology both presynaptically and postsynaptically, but the regulatory mechanisms remain obscure. To determine acute effects of proteasome inhibition on neurotransmission, we performed whole-cell voltage-clamp record...

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Detalhes bibliográficos
Main Authors: Rinetti, Gina V., Schweizer, Felix E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905680/
https://ncbi.nlm.nih.gov/pubmed/20203175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3712-09.2010
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