Integrated profiling reveals a global correlation between epigenetic and genetic alterations in mesothelioma

Development of mesothelioma is linked mainly to asbestos exposure but the combined contributions of genetic and epigenetic alterations are unclear. We investigated the potential relationships between gene copy number (CN) alterations and DNA methylation profiles in a case series of pleural mesotheli...

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Autors principals: Christensen, Brock C., Houseman, E. Andres, Poage, Graham M., Godleski, John J., Bueno, Raphael, Sugarbaker, David J., Wiencke, John K., Nelson, Heather H., Marsit, Carmen J., Kelsey, Karl T.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905466/
https://ncbi.nlm.nih.gov/pubmed/20587528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0190
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