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Inhibition of Iron Uptake Is Responsible for Differential Sensitivity to V-ATPase Inhibitors in Several Cancer Cell Lines

Many cell lines derived from tumors as well as transformed cell lines are far more sensitive to V-ATPase inhibitors than normal counterparts. The molecular mechanisms underlying these differences in sensitivity are not known. Using global gene expression data, we show that the most sensitive respons...

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Autori principali: Straud, Sarah, Zubovych, Iryna, De Brabander, Jef K., Roth, Michael G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905441/
https://ncbi.nlm.nih.gov/pubmed/20661293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011629
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