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The Runx transcriptional co-activator, CBFβ, is essential for invasion of breast cancer cells

BACKGROUND: The transcription factor Runx2 has an established role in cancers that metastasize to bone. In metastatic breast cancer cells Runx2 is overexpressed and contributes to the invasive capacity of the cells by regulating the expression of several invasion genes. CBFβ is a transcriptional co-...

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Detalhes bibliográficos
Main Authors: Mendoza-Villanueva, Daniel, Deng, Wensheng, Lopez-Camacho, Cesar, Shore, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905338/
https://ncbi.nlm.nih.gov/pubmed/20591170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-171
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