MUTATION OF THE HEXIM1 GENE RESULTS IN DEFECTS DURING HEART AND VASCULAR DEVELOPMENT PARTLY THROUGH DOWNREGULATION OF VEGF

Our previous studies and those of others indicated that the transcription factor Hexamethylene-bis-acetamide-inducible protein 1 (HEXIM1) is a tumor suppressor and cyclin-dependent kinase inhibitor, and that these HEXIM1 functions are mainly dependent on its C-terminal region. We provide evidence he...

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Detalhes bibliográficos
Main Authors: Montano, Monica M., Doughman, Yong Qui, Deng, Huayun, Chaplin, Laura, Yang, Jianqi, Wang, Nancy, Zhou, Qiang, Ward, Nicole L., Watanabe, Michiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905161/
https://ncbi.nlm.nih.gov/pubmed/18079413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.157859
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