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Superresolution Localization of Single Functional IP(3)R Channels Utilizing Ca(2+) Flux as a Readout

The subcellular localization of membrane Ca(2+) channels is crucial for their functioning, but is difficult to study because channels may be distributed more closely than the resolution of conventional microscopy is able to detect. We describe a technique, stochastic channel Ca(2+) nanoscale resolut...

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Detalhes bibliográficos
Main Authors: Wiltgen, Steven M., Smith, Ian F., Parker, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905071/
https://ncbi.nlm.nih.gov/pubmed/20643061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.037
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