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One-flask Syntheses of c-di-GMP and the [R(p), R(p)] and [R(p), S(p)] Thiophosphate Analogs

[Image: see text] An integrated set of reactions and conditions that allow an eight step one-flask synthesis of the protected derivatives of c-di-GMP and the [Rp,Rp] and [Rp,Sp] thiophosphate analogs is reported. Deprotection is also carried out as a one-flask procedure, with the final products isol...

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Detalhes bibliográficos
Main Authors: Gaffney, Barbara L., Veliath, Elizabeth, Zhao, Jianwei, Jones, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905038/
https://ncbi.nlm.nih.gov/pubmed/20572672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101236b
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