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Beyond Taxanes: A Review of Novel Agents That Target Mitotic Tubulin and Microtubules, Kinases, and Kinesins

Until recently, development of chemotherapeutic agents that target mitosis has centered on inhibiting the mitotic spindle through interactions with microtubules. The taxanes, while significantly advancing the treatment of many types of cancer, suffer from problems of hematopoeitic and neurologic tox...

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Библиографические подробности
Главные авторы: Harrison, Michael R., Holen, Kyle D., Liu, Glenn
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904974/
https://ncbi.nlm.nih.gov/pubmed/19274042
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