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Beyond Taxanes: A Review of Novel Agents That Target Mitotic Tubulin and Microtubules, Kinases, and Kinesins
Until recently, development of chemotherapeutic agents that target mitosis has centered on inhibiting the mitotic spindle through interactions with microtubules. The taxanes, while significantly advancing the treatment of many types of cancer, suffer from problems of hematopoeitic and neurologic tox...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904974/ https://ncbi.nlm.nih.gov/pubmed/19274042 |
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