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Wnt signaling regulates mitochondrial physiology and insulin sensitivity

Mitochondria serve a critical role in physiology and disease. The genetic basis of mitochondrial regulation in mammalian cells has not yet been detailed. We performed a large-scale RNAi screen to systematically identify genes that affect mitochondrial abundance and function. This screen revealed pre...

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Hlavní autoři: Yoon, John C., Ng, Aylwin, Kim, Brian H., Bianco, Antonio, Xavier, Ramnik J., Elledge, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904941/
https://ncbi.nlm.nih.gov/pubmed/20634317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1924910
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