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PUF3 acceleration of deadenylation in vivo can operate independently of CCR4 activity, possibly involving effects on the PAB1-mRNP structure
The evolutionarily conserved PUF proteins stimulate CCR4 mRNA deadenylation through binding to 3′ UTR sequences of specific mRNA. We have investigated the mechanisms by which PUF3 in Saccharomyces cerevisiae accelerates deadenylation of the COX17 mRNA. PUF3 was shown to affect PAN2 deadenylation of...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904828/ https://ncbi.nlm.nih.gov/pubmed/20435044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.034 |
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