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Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram

Elevated procoagulant levels have been correlated with increased thrombin generation in vitro and with increased venous thromboembolism (VTE) risk in epidemiological studies. Thrombin generation tests are increasingly being employed as a high throughput method to provide a global measure of procoagu...

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Detalles Bibliográficos
Main Authors: Machlus, Kellie R., Colby, Emily A., Wu, Jogin R., Koch, Gary G., Key, Nigel S., Wolberg, Alisa S.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904819/
https://ncbi.nlm.nih.gov/pubmed/19888532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH09-03-0180
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