Genome-Wide Screen in Saccharomyces cerevisiae Identifies Vacuolar Protein Sorting, Autophagy, Biosynthetic, and tRNA Methylation Genes Involved in Life Span Regulation

The study of the chronological life span of Saccharomyces cerevisiae, which measures the survival of populations of non-dividing yeast, has resulted in the identification of homologous genes and pathways that promote aging in organisms ranging from yeast to mammals. Using a competitive genome-wide a...

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Detalhes bibliográficos
Main Authors: Fabrizio, Paola, Hoon, Shawn, Shamalnasab, Mehrnaz, Galbani, Abdulaye, Wei, Min, Giaever, Guri, Nislow, Corey, Longo, Valter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904796/
https://ncbi.nlm.nih.gov/pubmed/20657825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001024
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