Endothelial Galectin-1 Binds to Specific Glycans on Nipah Virus Fusion Protein and Inhibits Maturation, Mobility, and Function to Block Syncytia Formation

Nipah virus targets human endothelial cells via NiV-F and NiV-G envelope glycoproteins, resulting in endothelial syncytia formation and vascular compromise. Endothelial cells respond to viral infection by releasing innate immune effectors, including galectins, which are secreted proteins that bind t...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Garner, Omai B., Aguilar, Hector C., Fulcher, Jennifer A., Levroney, Ernest L., Harrison, Rebecca, Wright, Lacey, Robinson, Lindsey R., Aspericueta, Vanessa, Panico, Maria, Haslam, Stuart M., Morris, Howard R., Dell, Anne, Lee, Benhur, Baum, Linda G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2010
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904771/
https://ncbi.nlm.nih.gov/pubmed/20657665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000993
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