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Intrinsically Disordered Regions May Lower the Hydration Free Energy in Proteins: A Case Study of Nudix Hydrolase in the Bacterium Deinococcus radiodurans

The proteome of the radiation- and desiccation-resistant bacterium D. radiodurans features a group of proteins that contain significant intrinsically disordered regions that are not present in non-extremophile homologues. Interestingly, this group includes a number of housekeeping and repair protein...

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Detalhes bibliográficos
Main Authors: Awile, Omar, Krisko, Anita, Sbalzarini, Ivo F., Zagrovic, Bojan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904767/
https://ncbi.nlm.nih.gov/pubmed/20657662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000854
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