Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci

BACKGROUND: Cellular senescence is a permanent growth arrest that occurs in response to cellular stressors, such as telomere shortening or activation of oncogenes. Although the process of senescence growth arrest is somewhat conserved between mouse and human cells, there are some critical difference...

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Bibliographic Details
Main Authors: Kennedy, Alyssa L, McBryan, Tony, Enders, Greg H, Johnson, F Brad, Zhang, Rugang, Adams, Peter D
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904742/
https://ncbi.nlm.nih.gov/pubmed/20569479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-5-16
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